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Article | IMSEAR | ID: sea-198556

ABSTRACT

Congenital Ichthyosiform Erythroderma- an extremely rare dermatological condition with an estimated incidenceof 1 in 50,000 to 100,000 birth. There is defective Stratum corneum barrier associated with collodion membranewhen the baby moves from an amniotic fluid to external dry environment during parturition. The membranedessicates and peels off. This condition is due to mutations in Transglutaminase1, ALOX genes, ABCA12, Ichthyin,ABHD5.

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